Presents research results (2019-2022) to assess the effectiveness of grain crop yield programming: soft spring wheat, spring barley, and oats using geoinformation technologies in satellite navigation applications. Experiments were conducted in the forest-steppe of the Novosibirsk Priob’ye region on leached chernozem in JSC livestock breeding farm “Irmen.”, Ordynsky district, Novosibirsk region. The authors programmed yields on the main grain crops: spring soft wheat varieties Novosibirskaya 31, spring barley Margret and oats varieties Rovesnik and Max. The use of balanced nutrition on the background of their differentiated application in combination with geoinformation technologies and satellite navigation helped to increase the parameters of average leaf area and FSP of soft spring wheat by 24%, spring barley by 22%, and oats by 27%.Fertilizer application on the programmed yield of 4.5-6 t / ha is efficient on the background of differentiated use of mineral fertilizers with justifiability yield programming 117%. The authors proved the dependence of grain crop yield on fertilizers by 38% and weather conditions - by 26% using a statistical method. Balanced doses of mineral nutrition at their differential application increased the protein content of cereal crops by 2%, starch by 4, fat by 0.1 and fiber by 0.2%. The use of yield programming has significantly increased its performance with good product quality. The efficiency of this agricultural technique in the system of optimal use of geoinformation technology with satellite navigation and drones averages 96%. This farming technique is cost-effective, and the level of profitability of production of major crops reached 182%.

In the process of growth and development, cultivated plants synthesize dry matter by removing mineral nutrients from the soil. Therefore, the root layer of cultivated plants must be rich in elements of mineral nutrition. Their economic removal as a result of alienation from the grown crop requires a return to the soil to increase its fertility and ensure the productivity of the upcoming harvest. The research aims to develop artificial grounds mixed with various local agricultural ores, ameliorants, and waste from agricultural and industrial production, including macro- and microelements. Studies were conducted under artificial conditions in the phytotron of Bashkir State Agrarian University. In the control variant, oats had the highest productivity and plant survival (57.0%), slightly lower - in spring wheat (43.0%), and the lowest - in pea (28.0%) because of potting soil acidity. The authors believe that the addition of zeolite to the soil increases the productivity of peas by 20.0%; spring wheat by 20.9; oats by 24.0%; with phosphogypsum by 38.0, 24.9 and 30.0%, respectively. The most effective in the experiments was the variant of potting soils with defecate. The growth in pea plants was 44.0%, spring wheat - 29.10 and oats - 234.0%. Potting soils and their components have excellent prospects in crop production in Russia.

. The authors studied the potato collection in 2019-2021 as part of a comprehensive research plan for the implementation of the subprogram “Development of potato breeding and seed production” based on SibNIIRS - a branch of the ICG SB RAS (Siberian Research Institute of Plant Growing and Breeding - a component of the Federal Research Center of the Institute of Cytology and genetics of the Siberian Branch of the Russian Academy of Sciences). The study aims to determine adaptive and high-yield potato varieties and their suitability for breeding. The authors presented the results of a survey of 13 potato varieties distinguished by productivity. The foreign variety Gala was taken as a standard since it is in the top ten cultivated areas in the Russian Federation.In 2019, the standard variety Gala had the highest yield among the tested varieties - 1653 g/bed. In 2020, all the studied varieties exceeded the standard; the authors note the maximum productivity in the following types: Terra (1067 g/bush), Kumach (1076 g/bush), and Prizer (1081 g/bush). In the last year of the study, two varieties significantly exceeded the standard variety: Terra (1280 g/bushel) and Sadon (1377 g/bushel). On average, over three years, the highest productivity was noted in the variety Alaska (1229 g / bush). Over the years of the study, 46% of the studied types distinguished themselves by their high productive ability and had an adaptability coefficient of more than 1. The authors note the highest value of the adaptability index in the variety Alaska (1.07). High marketability of tubers (over 97%) was observed in 11 out of 13 tested types. Low fertility and lack of natural berry formation in widely productive potato varieties make it difficult to use them in breeding for high productivity. In the foreststeppe conditions of the Novosibirsk Priob’ye region, the following types are suitable for breeding for increased productivity as pollinators: Salsa, Signal, and Gala having fertility from 50 to 90%. The authors also noted high natural berry production (7–9 points) in four varieties: Sadon, Prizer, Signal, and Gala. These varieties are recommended for the breeding process as mother plants.

The authors found that in long-term studies, the levels of damage to raspberries of the remontant type of fruiting by raspberry gall midge Resseliella theobaldi (Barn.), associated with mycosis - midge blight: the development of the disease ranges from 29 to 40%. Also, deep necrotization of the internal tissues of the stem (loss of commercial productivity) ranges from 15 to 28% of the total number of shoots. Therefore, gallic burn with an average and severe degree of damage significantly affects the growth, development, and productivity of annual shoots of remontant raspberries. In addition, gall midge burn reduces the total number of internodes formed by 10–15%, increases the number of vegetative nodes on the shoot by 13–32%, and reduces the length of the productive shoot by 12–17 cm. In addition, the diameter of the generative projection at the base is reduced by 14%, the number of generative organs is reduced by 1.4–5.2 times, the weight of 1 fruit is also reduced by 1.1–1.4 times, the productivity of 1 shoot also decreases by 1.6–5.4 times. The authors found that the severity of gall burn on a remontant weakly resistant raspberry variety can theoretically be calculated by a regression equation for the relationship between the level of disease development (X) and the degree of decrease in shoot productivity (Y): Y = -0.6395 + 0.6267X + 0.0019X², which allows interpolating estimates for any levels of damage to stands.

In the article, the authors presented those enticing actual herbicidal treatments (the active ingredient is cloquintocet-mexyl, fenoxaprop-P-ethyl), spring-summer and summer droughts, are stress factors for the development of early-ripening soybean varieties and zoned pea varieties in the forest-steppe of the Priobye region. They limit the realization of the biological yield potential of soybeans and reduce the coarseness of pea grains and their total protein. Use with the herbicide of humic preparation from leonardite Cytogumat at a rate of 0.4 l/ha relieves physiological stress on soybean plants, providing a rapid increase in biomass and grain yield of 4.2-5.5 c/ ha, or 19%. Furthermore, the humic product in a single year can increase the duration of soybean vegetation by 3-4 days and the height of lower bean attachment by 24%. The authors analyze the stress resistance to the anti-cereal herbicide of 5 varieties of peas. They also found that the varieties Altaysky Usatiy and Novosibirets mediumresistant, Yamal, and Astronaut are sensitive to the herbicide. The application of Cytogumat in susceptible varieties increased green mass by 30.1% and 24.0%, grain yield by 10.5-12.0%, weight of 1000 grains by 7.1-7.4%, and total protein. In moderately resistant varieties, the reaction to Cytogumat was less pronounced and was accompanied by an increase in yield by 8–10%, grain size by 5–5.4%, and protein content by 1.9%. The Yamalsky pea variety in the Ob River region proved to be tolerant to stress, and it is inexpedient to use Cytogumat on it.

The work aims to identify the most promising lines of own maize breeding on productivity and resistance to various environmental factors. It involves them in breeding work to create hybrids maize with an earliness index FAO 200-300. Maize is one of the major crops on the planet. This crop is associated with a high grain yield and, of course, with the versatility of use. One of the main conditions in increasing the production of a grain of corn hybrids is the study and identification of promising lines with high combination ability and the production of high-yielding mixtures on their basis. These hybrids are improved options for the breeding process, possessing economically valuable traits that are resistant to biotic and abiotic environmental factors. This work on getting and studying maize hybrids resistant to various factors (bio- and abiotic) is highly relevant for breeders of research institutions currently conducting research in maize breeding. The subject of research, investigations on the study of the selfed line of maize of own selection on economically valuable characteristics, as well as on resistance to biotic factors of the environment, were carried out. The authors laid out the experiments and evaluated the lines based on the institute in the foothill zone of Kabardino-Balkaria in 2020–2021. The authors carried out the experiments according to the methods of field experiments. According to the results obtained in the research, the following lines were distinguished: 92C0112, 92C5183, 92C543, 92C005, 92C0112, 92C5183, 92C267, 92C543, 92C06146, 92C5183, 92C267, 92C06146, 92C0206, 92C0241, which are of breeding value. According to yield data (from a working plot), the following numbers can be distinguished: 92C0247, 92C267, 92C281, and 92C0206. In the conditions of the foothill zone, the authors studied the lines of productivity and resistance of corn cobs to the primary diseases and pests found in the fields of the republic. This study was the scientific novelty of the research. Selected lines will be used in breeding work to obtain high-yield maize hybrids.

The need for unified approaches to determining the phenological phase of a reliable indicator of the vegetative index is one of the critical problems of early forecasting of crop yields using satellite monitoring. Several works of domestic and foreign researchers formulate different estimates of the correlation relationship between NDVI and yield. This study aimed to obtain predictive models for the product of winter wheat and spring barley using indicators that are adequate for formalizing the tasks of predicting the trend section of the vegetative index NDVI of crops within the experimental farm of the Oryol State Agrarian University. Based on the analysis of the dynamics of the vegetation index NDVI, based on multi-year studies, the maximum mean annual values of the vegetation index, 0.72 for winter wheat and 0.56 for spring barley, were determined.The maximum NDVI values of the 2021 season for these crops are 0.78 and 0.58. It was found that the peaks of NDVI values correspond to the earing phase of crops with possible variation from 1 to 13 days. The correlation coefficients between the maximum values of NDVI and productivity of crops were 0.79 and 0.75 for winter wheat and spring barley, respectively, which suggests the possibility of reliable prediction of crop yield based on the data of their peak NDVI values. The authors obtained predictive crop yield models based on polynomial (second-degree) functions. A reliable yield forecast expands the scope of reasonable estimates and the implementation of plans aimed at the progressive development of the individual farm. Furthermore, it contributes to the food security of Russia as a whole.

Within the framework of the grant “Creation of selection and seed production and breeding centers in agriculture to create and implement in the agricultural sector of modern technologies based on own developments of scientific and educational organizations” in 2021, the variety of spring barley Omsky 103 was transferred for state variety testing. The research aims to characterize the productivity and grain quality of the new promising Omsky 103. The study was conducted from 2017 to 2021. Optimal moisture conditions were represented in 2019 (GTC = 1.10), excessive moisture was observed in 2018, and dry conditions in 2017, 2020, and 2021 (GTC = 0.58-0.77). The new promising variety Omsky 103 (variety medium) belongs to the intermediate array, is a droughtproof variety, and has low susceptibility to black, stone, and dust smut. In the breeding record of sort Omsky 103, there are varieties and lines of breeding of Omsk Agrarian Research Center (Pallidum 3733, Medicum 4602, Medicum 4771, Ricotense 3928, Ricotense 3928, Ricotense 4432, Omsky 85, Omsky 89), other scientific centers of Russia (Belgorod K-22089, Cyclone, Kind, Olimp) and foreign breeding (Keystone). The advantages of the new variety Omsky 103 in terms of grain quality are higher protein content (13,27%; +0,15% towards the standard and +0,49% towards the type Omsky 102) and starch (56,41%; +0,62% towards the bar and +0,35% towards the variety Omsky 102). A positive characteristic of the array Omsky 102 is also an increased grain size (+10.04 g against the standard). Due to the increased yield (5.36 t/ha; +0.77 t/ha against the norm and +0.26 t/ha against the variety Omsky 102), the new perspective variety forms an increased grain harvest per unit area of protein (580.8 kg/a; +12.0% vs. standard and 22.5% to the Omsky 102) and starch (2.6 t/ha; +13.0% vs. standard and 21.7% to the variety Omsky 102).

Methods for forecasting genetic value in cattle breeding are widely recognized in countries with developed cattle breeding. They are used and improved in continuous evolution by genetic breeders and statisticians. The unbiased linear estimation method (BLUP/BLUE) is very flexible because it has many alternatives tailored to different breeding objectives, animal species, production conditions, and calculation methods. Today it is relevant to the search for new, faster, and more economical algorithms for inverting dominant and additive kinship relationships between individuals using additive kinship matrices. For a new search, it is necessary to select (create) a suitable selection model to solve the problem of cow culling, the non-random influence of sires. Further, it is essential to relate this to the fixed factors of the animal’s life cycle HYS (herd-year-season, herd-year-season) and the preferred production environment factors. The purpose of this paper is to address several issues related to the problems of animal breeding. First, an overview of a historically powerful method for assessing the genetic value of cattle (and other species by analogy) based on multifactorial regression models is presented, and simple examples of selection using it are given. Over the past decade, many new methodological techniques, programs, databases, patents, and review articles have been published in this area. By the requirements of national economic development, the material presented can serve as a guide for the study of new, modern methods of assessing the value of animals and the formation of new breeding indices.

In the article, the authors studied the structure of the herd and the signs of milk productivity of Redand-White cattle with different durations of production use. It was found that cows dominate the herd structure under three calves (70.25%). As cows age into calves of 4 to 10, the cow population decreases per lactation by 0.7 to 4.27%. The most numerous is the group of cows at the age of 1 calving (33.68%), and the least numerous is the group of cows at the age of 10 calvings (0.55%). The dynamics of milk yield in cows was positive from the 1st to the 3rd lactation by 5.6%. With increasing age in lactations 4 to 7, milk yields decreased by 0.48-9.9%. The authors noted the highest milk yield in cows of the 3rd lactation (6580 kg), which exceeded the average milk yield for the herd by 9.1%. The minimum milk yield was in cows of the 10th lactation (5637 kg), to the herd’s milk yield less by 6.6%. The fat content in milk was, on average, 0.35 percentage points higher than the breed standard, or 9.2%; the protein content in milk was 0.13 percentage points higher, or 4.3%. The degree of realization of the productive potential of cows depends on the level of productivity obtained over their entire production period. The average milk productivity of red-and-white cows in the breeding herd over the past three years was 6048 kg with productive use of 2.8 lactations. The average milk yield per cow during the effective period was 16934 kg, while the possible 24192 kilograms, 7258 tons of milk, were missed, worth 214546 rubles. The selling price is 29.56 rubles/kg of milk. For all controlled livestock, there was an average annual shortfall of 105386 ct of milk worth 3115210 rubles.

Studies were conducted in the period 2020-2021 based on the department of ecology and noncontagious pathology of animals of the Ural Veterinary Research Institute - a structural subdivision of FSBSI “UFARC UB RAS” (Federal State Budgetary Scientific Institution “Ural Federal Agrarian Research Center of the Ural Branch of the Russian Academy of Sciences”). Significant increases in ambient temperature in industrial poultry farming have natural and incidental effects on all processes in the living organism of birds, affecting their direction and intensity. We studied the use of feed additives containing dried live yeast of different variants and concentrations before and after heat stress on changes in the live body weight of laying hens, the importance of laid eggs, and quantitative and qualitative characteristics of the blood leukocyte formula. The authors registered a significant increase in the concentration of erythrocytes and hemoglobin in birds of the control group - 18.1 and 25.5% during the period of heat stress, which indicated the beginning of a long adaptation process.

Furthermore, the authors noted a significant increase in the ratio of the number of heterophils to lymphocytes (g/l) and in individuals of the control group by 44.2% (0.62 units), which confirmed the intensity of all processes in the body. During the study, the authors note that the total number of leukocytes increased against the background of a stress factor in the blood of laying hens of the control, 1st, and 2nd experimental groups - 1.4, 1.2, and 1.3 times, respectively. This increase occurs due to the release of immature heterophils into the bloodstream and the outflow of lymphocytes into peripheral tissues. The authors note the best stress resistance to 48-hour hyperthermia when using feed additives of hepatoprotective action in chickens of the 1st and 2nd groups reported the best stress resistance to 48-hour hyperthermia. This stress resistance is confirmed by regular physiological changes in the level of heterophils, basophils, monocytes, and G/L, characteristic of the period of urgent adaptation and maintenance of immune homeostasis.

Results of the evaluation of copper levels in the liver, kidneys, lungs, and spleen of Landrace pigs are presented. Studies were performed on clinically healthy six-month-old animals bred in a large pig farm in Altai Krai. Animal housing conditions were standard, typical for meat-fattening feeding was used. The authors performed an elemental analysis of samples of parenchymal organs using atomic absorption spectrometry with flame and electrothermal atomization. The data were processed using Microsoft Office Excel and the R programming language in the RStudio data analysis environment version 2022.07.2+576 (RStudio, PBC). It was found that the distribution in the case of copper accumulation in the kidneys and lungs was different from usual, and the dispersions were not homogeneous. Based on the mean value and median, the authors established an increasing ranked series of the copper content in the organs: spleen < lungs < kidneys < liver, in numerical terms: 1: 1.1: 6.4: 7.5. Median copper values in the liver, kidneys, lungs, and spleen were 6.25; 5.02; 0.88; and 0.83 mg/ kg, respectively. More excellent uniformity is characteristic of copper accumulation in the lungs and spleen. Using the Kraskell-Wallis criterion, we found that the collection of copper varies significantly in the organs under study (H = 80.03, df = 3, p < 0.0001). Pairwise comparison showed significant differences for pairs: “liver - lungs” (p < 0.0001), “kidneys - lungs” (p < 0.0001), “liver - spleen” (p < 0.0001), “kidneys - spleen” (p < 0.0001). Cluster analysis revealed two groups: “lungs - spleen” and “liver - kidneys,” which differ significantly in the level of copper accumulation. The data obtained can be used to calculate the corresponding standard values of the copper content in the liver, kidneys, lungs, and spleen of Landrace pigs under the conditions of Western Siberia.

The object of the study was Holstein cows of the second-fourth milk secretion and first-calf cows of different production groups formed depending on the physiological status of the animals. The most pronounced hematological changes were observed in sexually mature cows during the first three months of milk secretion. After fawning, the number of erythrocytes, lymphocytes, and hemoglobin decreased. The concentration of bloodforming elements in the groups with a first-calf cow was significantly higher than in sexually mature cows. The level of erythrocytes and hemoglobin in first-calf cows reaches its maximum value at the beginning of milk secretion. Sexually mature cows after the first month of milk secretion were statistically significantly superior to first-calf cows at the beginning of milk secretion in terms of granulocyte content. Cows, in the first days of milk secretion, had the most fantastic range of variability in the scope of erythrocytes, leukocytes, and hemoglobin, which reflects the individual response of the body to significant changes in physiological status. At the same time, the first-calf cows at the beginning of milk secretion had the most stable level of these hematological indices. Dry cows, as a rule, occupied an intermediate position regarding the variability of the content of blood form elements. Thus, assessing the hematological profile of cows of different production groups helps specialists make targeted adjustments to rations and housing conditions, effectively manage genetic resources and obtain high profits.

The study aimed to determine the characteristic changes in alimentary lymphoma in cats during ultrasonography, pathoanatomic and cytological examination of biopsy material. The survey objects are cats with gastroenterological disorders with suspected alimentary lymphoma of different ages and genders. The diagnosis was made based on a clinical examination according to generally accepted methods, laboratory blood examination, ultrasound examination, pathomorphological examination of the intestinal walls and lymph nodes, and cytological examination of the lymph node material obtained by the TIAB method. The authors carried out the material sampling for cytological examination using percutaneous fine needle aspiration (FNA) biopsy under ultrasound control on the Mindray Z6 Vet apparatus. In addition, the authors conducted pathological and cytological studies in the Vet Union laboratory. When analyzing ultrasound examination in cats diagnosed with alimentary lymphoma, hepatomegaly, 1% ascites, 3% hydrothorax, 3 % increase in mediastinal lymph nodes, 7% splenomegaly, 16% violation of differentiation of intestinal layers, 16% violation of differentiation of intestinal layers, 29% increase in mesenteric lymph nodes, 29 % thickening of intestinal walls were observed in 12% of cases. Cytological examination revealed rounded, large, separately located cells. The population is monomorphic. During a histological study in the intestinal wall, adjacent fatty tissue of the omentum, and lymph node tissue, there is a highly cellular invasive formation constructed from diffuse layers of rounded lymphoid neoplastic cells with a scanty fibrous stroma. The most characteristic ultrasound findings are the thickening of the intestinal walls and an increase in mesenteric lymph nodes.

The authors presented the results of a study of the feed additive’s effect on the gastrointestinal tract’s microflora, hematological, biochemical, and production indicators of piglets of the technological group 0-1 month of the Large White breed, Landrace, and Duroc. For the experiment, the authors formed two groups of animals - experimental and control. Piglets of the experimental group were fed with Bimulak Pre feed additive from the 2nd to the 15th day of life. Animals of the experimental group were on the usual diet and did not receive the feed additive. As a result of studies, a positive effect of feed additive Bimulak Pre on enterobiocenosis of the gastrointestinal tract of piglets, hematological and biochemical parameters of blood, and production performance. After the application, the feed additive helps increase the amount of beneficial microflora (bifidobacteria and lactobacilli) while reducing lactose-negative variants of Escherichia coli, staphylococci, and yeast-like fungi of the genus Candida in the intestine. Using the analysis of hematological and biochemical parameters, the authors found that the number of erythrocytes and hemoglobin slightly increased in the experimental group of piglets. In addition, the total number of incremental cytes decreases, the total protein content increases, and the glucose level decrease compared to the check. The use of the additive with the essential diet leads to a reduction in the mortality of piglets, increased preservation of young stock, and an increase in average daily live weight gain and average weight at weaning.

Presented research aimed at studying the energy-protein supplement’s effect on cows’ milk productivity. The authors conducted a scientific and economic experiment in 2021 based on the branch of the Siberian Research Institute of Fodder of Siberian Federal Research Center of Agrobiotechnologies of the Russian Academy of Sciences Komsomolskoye livestock breeding farm of Pavlovsky district of Altai region. The study was conducted on four groups of cows of the Ob river region type of Black-and-White breed. Lactation cows of the control group were given a basic ration with the addition of 1 kg of feed concentrate. In the primary allocation, the authors added an energy protein supplement to the main diet for experimental groups at 500 to 1000 g/head—per day. It included vegetable feed (distiller’s grain, oil cake and soybean meal, corn gluten, sunflower meal, lupine), animal meal (blood and poultry meat), yeast culture Saccharomyces cerevisiae (Y1242), synthetic methionine and lysine, organic chromium and unique flavor and aroma additives. The mechanism of action of the additive is aimed at increasing the intensity of digestion, optimizing protein and fat metabolism in the body, and ensuring the growth of the rumen microflora. The main qualitative parameters of the new energy-protein supplement: are crude protein - 60%, exchange interaction energy - 11.5 MJ, lysine - 1.8%, methionine - 0.3, calcium - 2.0, and phosphorus - 1.0%. Furthermore, feeding energy-protein feed supplements in diets positively affected the average daily milk yield of cows during the experiment period. Thus, the average daily milk yield in the experimental groups increased by 3.4-9.2 kg compared to the control group of animals. Therefore, according to the experiment results, it was found that the most optimal dose of energy-protein supplement should be considered 750 g/cow per day, which contributes to an increase in milk productivity throughout the experiment by 10.1% (P≤0.05).

The authors conducted the study based on the experimental quail farm SRDIAH SFSCA RAS (Siberian Research and Design Institute of Animal Husbandry Siberian Federal Scientific Center for Agrobiotechnology of the Russian Academy of Sciences) and at the Department of Obstetrics, Anatomy, and Histology of the Novosibirsk State Agrarian University. The study aims to change the content of micro- and macroelements in the blood of quails of the Japanese meat breed when using the Biocalcium feed additive. The productivity of animals depends on their health and is determined by their metabolism level. Birds, unlike other animals, have an intensive mineral metabolism.Calcium and phosphorus are two biologically active components with many functions that determine ana- and catabolic processes. When oviposition begins, the calcium and phosphorus concentration in chickens’ blood serum increases. But the rate of exchange of these macronutrients is determined by the activity of oviposition, so control over the content of these substances is relevant. Indicator enzymes that perform certain intracellular functions and enter the blood from the tissues are informative indicators for assessing metabolism. Using the activity index of alkaline phosphatase is reasonable to evaluate calcium-phosphorus metabolism. Using the feed additive Biocalcium in the blood of quail of the experimental group increased the calcium concentration by 0.2%. If we talk about zinc, iron, and magnesium indicators, they increased by 0.1-0.3%. It was also found that the introduction of fiber in feed rations had a definite effect on protein metabolism. During the experiment, it was found that the feed additive based on Siberian silver fir substrate Biocalcium has no apparent negative impact on the body of the quail. The additive is effective at a late stage of rearing. The authors note an improvement in metabolism, the mineral composition of the blood is normalized; hematopoiesis is stimulated without changing the stability of hematopoiesis and the constancy of the blood composition due to the introduction of this feed additive into the diet of birds.

In the article, the authors present the results of developing a feed mixture with the addition of the probiotic Levisel SB + in the production conditions of JSC Prodo Poultry Farm Permskaya. In the poultry body, due to intensive industrial rearing, fattening, change of diet, and composition of feed mixtures, the fermentation process in the large intestine of poultry is disturbed. Therefore, it is crucial to develop feed mixes with various supplements, probiotics, and prebiotics—one of the most important criteria for obtaining quality poultry meat - complete fodder. Mixed fodder is a feed mixture of purified finely chopped raw materials of plant and animal origin with the addition of enriching substances such as vitamins, micro-, and macronutrients, enzymes, probiotics, and more. To date, our task has become not only the production of quality feed but adding to them such ingredients that would increase meat productivity, ensure the health of poultry and obtain environmentally friendly products. Prodo agro holdings growing poultry production volumes are ahead of the national average. First of all, this increase is connected with investment projects. In 2008 Prodo agricultural holding developed and introduced national brands “Rokoko” and “Troekurovo,” which allowed the company to expand the geography of sales of its products. Currently, there is a trend towards increased consumption of poultry meat both in the Russian Federation and the global community. Under these conditions, simply producing high-quality poultry feed is not enough. Therefore, the authors propose to include the probiotic Levisel SB+ in poultry diets, a bacterial concentrate containing beneficial microorganisms with high enzymatic activity. This probiotic increases the quantity and improves the quality of products in the conditions of JSC “Prodo Poultry Farm Permskaya.”

The main trends in the development of animal husbandry in the Republic of Kalmykia are considered. It is necessary to carry out the current selection to preserve and improve the genetic potential of animals. In the Republic of Kalmykia, immunogenetic expertise is effectively used in cattle breeding. The purpose of the study was to analyze statistical data on Kalmyk cattle in 1988 and 2018. It was found that the number of livestock increased by 324430 heads over 30 years. A comparative analysis of the exterior data of the animals showed that the bulls-producers in 2018 were more extensive compared to 1988: The difference in withers height was 1.6%, body length was 1.2, chest girth was 1.9, and cannon bone circumference was 5.7% (P<0.95). Positive dynamics were also observed in cows. The average live weight of sire bulls in 2018 was 796.7±3.7 kg, 35.2 kg (4.6%) higher than that of animals in 1988. Cows in 2018 outperformed 1988 animals by 26.1 kg (5.7%) in live weight (P><0.95). I’, C2, L’, and S2 antigens had met less frequently. I’, C2, L’, and S2 antigens had met less frequently. Thus, we can state that for 30 years, there have been changes in the frequency of occurrence of antigens in breeding farms and, consequently, changes in the gene pool. When comparing the increase and decrease in the frequency of occurrence of antigens between the two breeding farms, there are apparent differences, indicating a multidirectional selection.>˂0.95). Positive dynamics were also observed in cows. The average live weight of sire bulls in 2018 was 796.7±3.7 kg, 35.2 kg (4.6%) higher than that of animals in 1988. Cows in 2018 outperformed 1988 animals by 26.1 kg (5.7%) in live weight (P˂0.95). I’, C2, L’, and S2 antigens had met less frequently. I’, C2, L’, and S2 antigens had met less frequently. Thus, we can state that for 30 years, there have been changes in the frequency of occurrence of antigens in breeding farms and, consequently, changes in the gene pool. When comparing the increase and decrease in the frequency of occurrence of antigens between the two breeding farms, there are apparent differences, indicating a multidirectional selection.

Today, goat breeding is characterized by intensive development, the rapid development of technology, and an active increase in goat productivity. The genetic potential of under-hair goats allows to increase production, but certain limiting factors exist. Therefore, research is needed to identify and select goats with the highest productivity indicators. The article presents the results of research conducted in natural climatic conditions of the Orenburg region to study the peculiarities of skin and integumentary hands of goats of the Orenburg breed of different types (Orenburg, desirable and downy) to develop methods of improving the productive indicators of goats and the quality of goat breeding products. Studies were conducted in the Orenburg region’s agricultural production cooperative “Donskoy” Belyaevsky district. The resulting information determined the characteristics of the indicators of the skin and hairline and the level of productive qualities, depending on the individual genetic factors of goats. Also, this information will make it possible to determine the coat type’s effect on productivity indicators and contribute to developing a method for selecting Orenburg goats to realize their genetic potential during breeding. According to the results of individual chess, the authors received more under hair from down-type goats. They surpassed the Orenburg-type goats by 25.25% in this indicator, the desired type peers by 5.87%, and Group 2 individuals outperformed the Orenburg-type peers by 20.58%. Furthermore, it was found that there are specific intergroup differences in the elongation and tensile properties of down fibers.

Due to the high intensity and profitability of production, pig breeding is an engaging activity for both large agricultural enterprises and farms. Today, however, all the production growth comes from large pig farms and complexes. The share of small-scale farms decreases annually due to the need for modern scienceintensive technical and technological planning solutions that reduce labor costs and maximize the use of animal genetic potential. To solve this problem, the authors have developed a project and manufactured a prototype of a technological module for fattening pigs. The fattening period of pigs was 100 days from the age of three months. Studies showed that average daily gains ranged from 520 to 906 g and feed conversion ratio from 3.05 to 3.6 depending on the year. The consumption of water, electricity, and labor required for animals to gain 1 kg of live weight varied in the range of 6.54-8.25 liters/kg, 0.028-0.069 kWh/kg, and 0.031-0.064 person-hours/kg, respectively. The content of harmful gases such as CO2, NH3, and H2S generally complied with the maximum permissible concentrations, except for some time intervals during the cold season, so it was proposed to install an additional forced air extraction system during this period. The effectiveness of using the developed technological module on small-scale commercial enterprises, based on the obtained technical and economic indicators, is comparable to the hands of large pig farms.

This article reflects on the issue of adequate poultry feeding and the case of refusing antimicrobial drugs when growing broiler chickens. Antimicrobials use in poultry diets is directly related to the actual problem of our time - antibiotic resistance. Many antibiotics, actively used in poultry farming before, gradually lose their effectiveness - bacteria begin to suppress their action and even completely neutralize the medicine. Diseases start to occur in a more acute form. The theoretical and practical significance of the study is based on the rejection of antimicrobial drugs when a probiotic pill with antagonistic properties to pathogenic microorganisms is added to the diet of broiler chickens. The article presents the key points of the study and the results of laboratory and practical experiments to identify the antagonistic activity of a probiotic preparation based on bacillus amyloliquefaciens to pathogenic microorganisms. The research methods on which this article was based are laboratory and practical experiments, scientific and economic experiments, and statistical data analysis. The first stage of research is laboratory tests confirming the drug’s antagonistic activity and the active substance’s survival when passing through the acidic environment of the bird’s stomach. The second research stage was a scientific and economic experiment on a small number of broiler chickens. The authors proved the antagonistic activity of the probiotic preparation based on bacillus amyloliquefaciens based on the results of this study. In addition, the authors confirmed the possibility of using the drug in the diets of broiler chickens as an alternative to antimicrobials.

The Republic of Bashkortostan is one of the regions of Russia where historically, there are favorable landscape and climatic conditions for developing the beekeeping industry. The territory of the Toratau Geopark has incredible biodiversity. Bees are pollinators of entomophilous plants, which, in turn, affects the productivity of berry and fruit plants and contributes to the revival of the natural flora of forest resources. However, only 360 thousand hectares of nectar-producing linden are growing in the three-kilometer zone of apiaries, and the rest are located in inaccessible areas of the republic.Unfavorable weather conditions do not allow for productive honey harvesting during the linden blossom period. Hence, the research aimed to determine the honey productivity of plant formations in the territory of the Toratau Geopark. The results of the studies showed that high honey productivity is characterized by gnat’s linden (574.4 kg/ha) and nettle twigs (458.1 kg/ha). Maplewood formation is a source of abundant honey harvesting in the spring period, with honey productivity of the forest type of the gnarly forest - 350.4 kg/ha, prickly-bristled barry forest - 332.3 kg/ha. In early spring, floodplain elm with significant honey productivity (254.3 kg/ha) and bramble elm (252.3 kg/ha) provide supportive honey collection and build-up of bee family strength. The knowledge gained about the honey productivity of plant formations in the study area is a scientific contribution to the rational use of honey resources in the territory of Bashkortostan. Also, these studies help preserve the natural flora of forest resources, optimize the population, expand the range, and maintain the genetic purity of the people of the native Burzyan wild bee (Apis mellifera L.), as well as for obtaining productive honey collections.

In the article, the authors conducted a comprehensive study of the interior, including biochemical, physiological, physicochemical, cytogenetic, and other indicators in sheep of the Romanov breed of Western Siberia. For the study, blood serum samples were taken from 10 rams-producers and 30 lambs at four months. Conventional methods took blood samples. Analyses were performed in the biochemistry laboratory of Novosibirsk State Agrarian University using the technique of competitive enzyme immunoassay with the reagent kit “SteroidIFAtestosterone” for the quantitative determination of testosterone concentration in blood serum. In the sheep breeding area, the authors constantly monitored the content of heavy metals in water, soil, feed, organs, and tissues. The concentration of chemical elements did not exceed the permissible exposure limit. Enzyme-linked immunosorbent assay was performed on a Thermo Scientific Multiskan FC analyzer. The authors performed statistical processing of experimental data using standard methods of descriptive statistics, the statistical programming language, or the RStudio data analysis environment (using the functions DescrStats, Summary, Sd, Read. Table, Write. Table, Aes). The authors established the influence of the age of ontogenesis on the testosterone content in Romanov rams. Presented figure with two variation curves with high transgression. The average testosterone level was 1.8 times higher in lambs (0.774 mmol/l) than in lambs. Testosterone concentration was characterized by high phenotypic variability. The authors have identified reference intervals for testosterone in blood serum depending on environmental conditions in sheep of the Romanov breed of Western Siberia.

Studies on the genotypic structure of the Altai white down breed by BLG, IGF-1, and CSN3 genes are presented. Genomic DNA was isolated from the blood of 113 animals using the Amplie Prime DNA-Sorb-B clinical extraction kit. Molecular genetic reactions were performed on a C1000 BioRad amplifier. Visualization and identification of the results were determined by flatbed electrophoresis in 2% agarose gel using the E-BoxCX5.TS-20.M gel-documentation system (France) in transmitted ultraviolet light. As a result, the frequency of genotypes and alleles was established as follows: BLG^S1S1 – 17,7%, BLG^S1S2 – 57,5, BLG^S2S2 – 24, respectively; BLG^S1 – 0,46; BLG^S2 – 0,54; IGF^AA – 2,7; IGF^AB – 28,3 и IGF^BB – 69,0%. The allele frequencies are IGF^A – 0,17 and IGF^B – 0,83. The CSN3 gene in Altai white down goats was monomorphic for the CSN3^А allele. Analysis of the actual and theoretical distribution of BLG and IGF1 genotypes of goat genes indicates a genetic equilibrium in the flock. The down productivity of the studied animals is fleece - 680 g, down fineness -19.13 microns, and down length - 9.29 cm. Goats with the IGF^AB genotype have more wool than the homozygotic IGF^AA genotype. The fat content of the milk ranges from 6.03-6.24%, the protein content is 3.48-3.72%, and the lactose content is 4.56-4.90%. The study of milk quality indicators of Altai white down goats with different genotypes of BLG, IGF, and CSN3 revealed no significant differences. However, goats tend to increase milk fat and caloric content with the IGF^AA genotype - 7.62. The studied goats of the Altai white down breed had a high equilibrium of indicators by live weight, length of down, down content in percentage, and down fineness - Cv˂10%.