ESTIMATION OF CHANGES IN THE LEUKOGRAM WITH MAMMARY GLAND TUMORS IN DOGS

Abstract

The paper examines the influence of ecological conditions in dogs’ habitat upon the relationship between the number of periphery blood leukocytic cells and tumor stage in mammary gland new formations. It is established that there is leucocytopenia in the dogs with mammary gland tumor (MGT) at stage I, leukocytosis at stage III and leukocytes level varies within the norm at stage IV. MGT progress stage influenced the percentage portion of cells in leukogram. At MGT progress stage III, leukoformula readings varied within the norm except for eosinophils level exceeding the high value by 49.3 %; MGT stage III was characterized by leukocytic cells rearranged within the norm in the leukogram and it was at MGT progress stage IV that neutrophill leococytosis with «leftward» degenerative shift, eosinophilia and lymphocytopenia were marked. Sensibilizing action of tumor and tumor antigens onto the bitch body reflected the value of eosinophil and allergization indexes (EI and AI). The progress of tumor growth was concomitant with growing EI and declining AI values.