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The effect of fulvic acid on the biochemical status of mature dry cows

https://doi.org/10.31677/2072-6724-2025-77-4-197-203

Abstract

Summary An integral part of the effective production of agricultural products is the full-fledged feeding of animals, for which various feed additives are used. Biologically active substances of natural origin, which are more suitable for the animal body, are non-toxic and have no side effects, in particular fulvic acid, have an undoubted priority among them. The article examines the effect of the use of fulvic acid in the diets of pregnant cows on the biochemical parameters of blood serum. The experimental part of the work was carried out in the farm Ermolinskoye in the Novgorod region on the stock of old-age dry-resistant Holstein cows. Three groups of animals were selected (n=10), the control group consumed a basic nutritionally balanced diet (RR) for this category, the first experimental group consumed RR + fulvic acid (20 ml/head/day), the second experimental group consumed RR + fulvic acid (25 ml/head/day). The research results showed that the concentration of the studied metabolic products in the blood of animals was mostly in the range of normal values, but there were intergroup differences. Thus, an analysis of the parameters of the protein index showed that the use of fulvic acid in a dosage of 25 ml in the diet led to a decrease in its value below the recommended values, and amounted to 0.84 versus 0.9 in the control and first experimental groups. An increase in the mass dose of the supplement to 25 ml also led to a decrease in the urea content in the blood serum compared with these groups. The decrease in the ratio of AST to ALT in the experimental groups, especially in the first one, can be regarded as a reduction in pathological changes in the liver and a manifestation of the hepatoprotective therapeutic effect of fulvic acid. The study of experimental data allows us to conclude that the use of fulvic acid in the diets of deeply pregnant cows did not have a critical effect on the composition of blood serum. The results obtained allow us to recommend fulvic acid for use in the diets of deeply pregnant cows on farms in the North-Western region in the amount of 20 ml per head per day.

About the Authors

T. B. Lashkova
Novgorod Scientific Research Institute of Agriculture, a branch of the St. Petersburg Federal Research Center of the Russian Academy of Sciences
Russian Federation

Candidate of Agricultural Sciences

Borki



G. V. Petrova
Novgorod Scientific Research Institute of Agriculture, a branch of the St. Petersburg Federal Research Center of the Russian Academy of Sciences
Russian Federation

Senior Researcher

Borki



References

1. Bezuglova O.S., Zinchenko V.E., Achievements of science and technology of the agroindustrial complex, 2016, Vol. 30, No. 2, pp. 89–93. (In Russ.)

2. Valitov Kh.Z., Frolkin A.I., Sovremennaya veterinarnaya nauka (Modern veterinary science: theory and practice), Materials of the International scientific and practical Conference, Izhevsk, 2020, pp. 269–273. (In Russ.)

3. Vasiliev A.A., Korobov A.P., Moskalenko S.P. [et al.], Agrarian Scientific Journal, 2016, No. 3, pp. 13–16. (In Russ.)

4. Bai H., Chang Q., Shi B., Shan A., Effects of fulvic acid on growth performance and meat quality in growing-finishing pigs, Livestock Science, 2013, Vol. 158, pp. 118–123, DOI: 10.1016/j.livsci.2013.10.013.

5. Chang Q., Lu Z., He M., Gao R., Bai H., Shi B., Shan A., Effects of dietary supplementation of fulvic acid on lipid metabolism of finishing pigs, Journal of animal science, 2014, Vol. 92 (11), pp. 4921–6, DOI: 10.2527/jas.2014-8137.

6. Garcia J., Pempek J., Hengy M., Hinds A., Diaz-Campos D., Habing G., Prevalence and predictors of bacteremia in dairy calves with diarrhea, J Dairy Sci, 2022, Vol. 105 (1), pp. 807–817, DOI: 10.3168/jds.2020-19819, PMID: 34656356.

7. Dai C., Xiao X., Yuan Y., Sharma G., Tang S., A Comprehensive Toxicological Assessment of Fulvic Acid, Evid Based Complement Alternat Med, 2020, pp. 8899244, DOI: 10.1155/2020/8899244, PMID: 33381216, PMCID: PMC7758121.

8. Murbach T.S., Glávits R., Endres J.R., Clewell A.E., Hirka G., Vértesi A., Béres E., Pasics Szakonyiné I., A toxicological evaluation of a fulvic and humic acids preparation, Toxicol Rep, 2020, No. 7, pp. 1242–1254, DOI: 10.1016/j.toxrep.2020.08.030, PMID: 32995299, PMCID: PMC7505752.

9. Hassan A.A.M., Salem A.Z.M., Elghandour M.M.Y., Abu Hafsa S.H., Ravi Kanth Reddy P., Atia S.E.S., Vidu L., Humic substances isolated from clay soil may improve the ruminal fermentation, milk yield, and fatty acid profile: A Novel approach in dairy cows, Animal Feed Science and Technology, 2020, Vol. 268, pp. 114601, DOI: 10.1016/j.anifeedsci.2020.114601.

10. Wang D., Du Y., Wang S., You Z., Liu Y., Effects of sodium humate and glutamine combined supplementation on growth performance, diarrhea incidence, blood parameters, and intestinal microflora of weaned calves, Animal Science Journal, 2021, Vol. 92 (1), pp. e13584, DOI: 10.1111/asj.13584.

11. Gromyko E.V., Ecological Bulletin of the North Caucasus, 2005, No. 2, pp. 80–94. (In Russ.)

12. Aschenbrenner A.I., Belyaeva N.Yu., Chekunkova Yu.A. i dr., Bulletin of KrasGAU, 2023, No. 10, pp. 202–207, DOI: 10.36718/1819-4036-2023-10-202-207. (In Russ.)

13. Velikanov V.V., Marusich A.G., Sudenkova E.N., Animal husbandry and veterinary medicine, 2021, No. 1, pp. 3–9. (In Russ.)

14. Kulakov V.V., Saitkhanov E.O., Fedosova O.A. et al., Bulletin of the Ryazan State Technical University named after P.A. Kostychev, 2021, No. 4 (13), pp. 73–82. (In Russ.)

15. Ovsyannikov A.I., Osnovy opytnogo dela v zhivotnovodstve (Fundamentals of experimental business in animal husbandry), Moscow: Kolos, 1976, 185 p

16. Plokhinsky N.A., Rukovodstvo po biometrii dlya zootekhnikov (Guide to biometrics for animal technicians). Moscow: Kolos, 1969, 256 p.


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For citations:


Lashkova T.B., Petrova G.V. The effect of fulvic acid on the biochemical status of mature dry cows. Bulletin of NSAU (Novosibirsk State Agrarian University). 2025;(4):197-203. (In Russ.) https://doi.org/10.31677/2072-6724-2025-77-4-197-203

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ISSN 2072-6724 (Print)