CHANGED BLOOD INHIBITORY POTENTIAL IN DOGS WITH MAMMARY GLAND TUMOUR DAMAGES
Abstract
The study is carried out in blood inhibitory potential in dogs with malignant and benign new formations in the mammary gland. It is established that the malignant course is characterized by increased and decreased activity in α1- inhibitor of proteinases in 75 and 25 % cases, respectively. With the benign neoplasms the indexes mentioned make up 42 and 58 %. Mean levels (increased / decreased activity) are marked: 119.43 ± 17.83/63.92 ± 7.94 mcmol/l - in malignant tumor patients; 141.45 ± 14.11/59.88 ± 9.27 mcmol/l - in benign tumor patients. Physiological indexes exceeded by 50 % were registered in 43.75 % of dogs in the first case; as for the second one, they were 36.85 %. The data obtained from the examination in the level of the α1- inhibitor of proteinases in the blood of dogs with mammary gland neoplasm damages indicate the presence of the inhibitor’s significant changes which characterize the features of tumor process course and are the rationale for the use of an extra estimation criterion when mammary gland having neoplasm (diagnostics at early stages, «behavior» estimation, therapy quality control).
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Review
For citations:
CHANGED BLOOD INHIBITORY POTENTIAL IN DOGS WITH MAMMARY GLAND TUMOUR DAMAGES. Bulletin of NSAU (Novosibirsk State Agrarian University). 2014;2(31):110-113. (In Russ.)
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