Influence of processings anti-parasitic drugs on hematological parameters and titer antiviral antibodies at BLV-infective horned cattle

Abstract

The changes of hematological parameters and titer antiviral antibodies at BLV-infective calfs after introduction Ivermec are analysed. At infected at virus leukemia calfs, reacting in reaction immunodiffusion are occurred authentic decrease in quantity of leukocytes and lymphocytosis in blood (Р < 0,05), reaching the maximum for 7th day after preparation introduction. Thus the quantity neutrophilia for 3-7th days (Р < 0,05) simultaneously has authentically raised. By 14th day of supervision indicators have returned to reference values before preparation introduction. At not reacting in reaction immunodiffusion calfs after introduction Ivermec similar changes were smoothed and doubtful. At control reacting and not reacting in reaction immunodiffusion calfs which did not enter Ivermec, authentic changes in hematological parameters it is not revealed. The tendency to some decrease in a caption of antibodies to a virus leukemia in reaction immunodiffusion at infected calfs for all period of supervision till 28th day after introduction Ivermec (to 3,75 log2) is noted. At control infected calfs, reacting in reaction immunodiffusion whom did not enter Ivermec, a caption of antibodies to a virus leukemia was a little above (to 5,00 log2; P > 0,05). Taking into account the revealed changes in blood calfs after introduction Ivermec following recommendations to terms of carrying out of diagnostic laboratory researches on leukemia a horned cattle are offered. After introduction Ivermec carrying out hematological researches at horned cattle on leukemia should be begun not earlier than in 14 days. Carrying out serological researches at horned cattle in reaction immunodiffusion on leukemia should be begun not earlier than through for month after introduction Ivermec, because of possible decrease in a caption of antibodies and appearance of false negative reactions.