DYNAMICS OF GROWTH IN THE GOUSES UNDER CONDITIONS OF THE COMBINED PHARMACOPROPHYLACTIC HOMOBIOTICS, PROBIOTICS BASED ON THE RECOMBINANT BASILL AND ENROFLOXACIN STRAIN

The combined effect of homobiotics, probiotics based on recombinant strains of g. Bacillus, & enrofloxacin on the dynamics of body weight gain in geese was studied. According to the principle of steam-analogs, one control and five experimental groups of 10 goslings in each group were formed. Gosyatam experimental groups used homobiotics vetom 15.1; vetom 13.1 incombination with enrofloxacin followed by replacement with a probiotic preparation Vetom 1.2. The absolute body weight and average daily gain in geese under the influence of the studied drugs increases. The severity of the effect depended on the pharmacological composition of the drugs used. The maximum absolute weight gain was observed when using the drugs according to the scheme: vetom 13.1 at doses of 25–50 mg/kg for 16 days, with further use of a 10% enrofloxacin solution at a dose of 0.5 ml/kg for 5 days and in The experiment period was 1.2 at a dose of 50 mg/kg for 16 days. After the cessation of the use of drugs, the growth rate increased for 30 days when prescribing the drugs according to the scheme: veto 13.1 at a dose of 50 mg/kg for 16 days and with further introduction of homobiotic veto 1.2 into the bird in a dose of 50 mg/kg for 16 days. The maximum average daily gain in live weight of geese was observed in the period from the 16th to the 32nd day with the administration scheme: homobiotic vetom 13.1 at a dose of 25 mg/kg of body weight 1 time per day for 5 consecutive days, then every other day for 16 days, then daily 10 % solution of enrofloxacin at a dose of 0.5 ml/kg of body weight for 5 days, then vetom 1.2 at a dose of 25 mg/kg once a day for 16 days in a row. And the maximum average daily gain in the post using period of the drug was observed on the 32^nd day of the study according to the scheme: homobiotic veto 15.1 at a dose of 50 mg/kg of body weight 1 time per day for 16 days, then daily with vetom 1.2 at the same dose 1 once a day for 16 days. The studied drugs in the applied doses did not have a toxic effect on the physiological state of geese.

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